Case sharing and prevention and treatment plan for neurological symptoms in 4-day-old newborn piglets
Neurological symptoms appear in 4-day-old newborn piglets, case sharing + prevention and treatment plan
Case: On May 3, Mr. Li, who runs a farm with 30 sows in Nanyang, Henan, sent a video seeking diagnosis. The farm has always been self-breeding and self-raising. Recently, several sows in a row gave birth to piglets that at 4 days showed individual pigs vomiting, yellow diarrhea, swollen eyelids, inability to stand, and paddling movements. More than 20 piglets have already died. He hoped the author could visit for diagnosis. After the author arrived at the site, there were still 17 piglets showing symptoms.
Necropsy changes: The piglets had suppurative ulcerative lesions in the tonsils, white necrotic foci in the liver, white necrotic foci in the spleen, and a small number of hemorrhagic spots in the kidneys.
Case diagnosis: Based on analysis of the clinical symptoms and necropsy changes, it was determined to be porcine pseudorabies.
TreatmentPlan: For the affected piglets, 1 dose of pseudorabies gene-deleted vaccine was administered by nasal drip, and other unaffected newborn piglets were given 1 dose by nasal drip at 2 days of age. After nasal drip, 3 of the affected piglets basically died three days later, and the other piglets had already recovered.
Case analysis: The sows on this pig farm had always been given routine pseudorabies vaccination twice a year, and the farm housed pregnant sows and lactating sows in the same pen, which increased the risk of infection. After the disease occurs in a pig herd, it is necessary to diagnose early and treat early,treatment, and promptly adopt comprehensiveprevention and controlmeasures so that the outbreak can be brought under control early. The farm's immunization plan and immunization program were incomplete and need to be improved.
Clinical symptoms of this disease: The stage of affected pigs differs, and the symptoms shown vary.
A. Manifestations in pregnant sows
① When pseudorabies occurs in pregnant sows, it is mainly in the late stage of gestation, manifesting as abortion, stillbirth, and mummified fetuses.
② The aborted fetuses are relatively uniform in size.
B. Lactating piglets: Starting after the 3rd day after birth, piglets may show fever, depression, vomiting, yellow diarrhea, swollen eyelids, ataxia, epilepsy-like convulsions, and other neurological symptoms.
C. Nursery pigs and finishing pigs: Mainly manifest as respiratory symptoms such as sneezing, coughing and panting, and nasal discharge.
Summary analysis: There is no specific drug for pseudorabies, and vaccine immunization is mainly used. Porcine pseudorabies virus works by occupying sites. Once wild-type pseudorabies virus occupies the epithelial cells of the pig's nasal and respiratory mucosa, the herd is prone to disease when resistance is low. At 2-3 days of age, piglets are given 1 dose of pseudorabies vaccine by nasal drip to occupy the respiratory epithelial cells, so wild-type virus cannot invade the body. According to the farm's situation, formulate a reasonable vaccine immunization program and strengthen immunization with genetically engineered pseudorabies vaccine. (Source: Toutiao, Veterinarian Lao Xu)