How do you detoxify a pig after metronidazole poisoning caused by feeding it distiller's grains?

First we need to understand why a pig that has been given metronidazole and then eats distiller's grains becomes poisoned.

Only then can we treatthe cause. Different types of poisoning require differenttreatmentmeasures.

As the questioner says, the pig ate distiller's grains, and distiller's grains, as a cost-effective feed, are rich in fat and protein, and also contain large amounts of B vitamins, which can promote digestion and absorption and promote growth in pigs.

As a by-product of distilleries, distiller's grains contain some alcohol. Under normal circumstances, after the pig eats the alcohol in the distiller's grains, it is detoxified in the liver: first, the alcohol is broken down into acetaldehyde under the action of alcohol dehydrogenase, and the acetaldehyde is broken down into acetic acid under the action of acetaldehyde dehydrogenase. It should be noted that acetaldehyde is biologically toxic, while acetic acid is not.

But if the pig has orally taken metronidazole at this time, it triggers a biochemical reaction called "disulfiram-like reaction", which interferes with the activity of acetaldehyde dehydrogenase in the body, so that the acetaldehyde in the pig's body cannot be converted into acetic acid, causing acetaldehyde to accumulate in the pig's body and leading to poisoning, which can be fatal in severe cases.

If poisoning occurs in the pig herd, first immediately stop feeding the distiller's grains. Give the pigs glucose and VC in their drinking water.

First, through drinking a large amount of water, the alcohol and excess acetaldehyde in the body are metabolized out through urine.

Second, glucose and VC have the effect of protecting the liver and detoxifying.

Third, it should be noted that when using distiller's grains as feed, the amount must be controlled, and distiller's grains must never be fed alone. Because in addition to alcohol poisoning, distiller's grains can also cause acidosis in pigs, triggering gastroenteritis and gastric ulcers.