Key Technical Points and Detailed Explanation of Epidemic Prevention Methods for Swine Disease Immunization

Reference Immunization Program

1 Vaccines Recommended for General Inoculation

1.1 Classical Swine Fever Immunization

Newborn piglets receive their first vaccination with the conventional dose of lapinized attenuated classical swine fever virus vaccine at 20 days of age. (It is best to promote zero-time pre-immunization.)

Piglets at 50-60 days of age receive the routine second immunization.

Selected replacement pigs receive a third immunization before participating in mating.

1.2 Swine Paratyphoid Immunization

The entire herd of adult and replacement pigs are immunized at conventional doses in March of spring and September of autumn.

Piglets over 30 days of age are individually vaccinated with the conventional dose.

1.3 Swine Erysipelas and Swine Pasteurellosis Immunization

The entire herd of adult and replacement pigs are immunized at conventional doses in March of spring and September of autumn.

Replacement pigs receive a supplementary inoculation in June-July of the following year.

At 60-75 days of age, vaccinate with the conventional dose per head (or use the classical swine fever-erysipelas-pasteurellosis combined vaccine).

1.4 Japanese Encephalitis

In epidemic areas, vaccination is carried out 1-2 months before mosquitoes and flies appear each year.

1.5 Immunization against Blue Ear Disease (PRRS), Pseudorabies, and Porcine Parvovirus Disease

Apply the "Blue-Parvo-Pseudo Triple Inactivated Vaccine." Replacement gilts are immunized by intramuscular injection 2-3 weeks before mating; piglets are immunized by intramuscular injection at 3-4 weeks of age; a second immunization is given after weaning.

1.6 Piglet Yellow and White Scours

Use the "Piglet Escherichia coli ST1-LTB-K88 Trivalent Genetically Engineered Vaccine." First-farrowing sows receive one intramuscular injection each at 40 days and 15 days before farrowing; multiparous sows receive one intramuscular injection at 15 days before farrowing; piglets receive an intramuscular injection at 7 days of age.

1.7 Edema Disease

Apply the "Swine Edema Disease Inactivated Vaccine" to piglets by intramuscular injection at 14-18 days of age.

1.8 Swine Streptococcosis

It is best to use the "Local Strain Inactivated Vaccine." In epidemic areas (farms), the first immunization is given at 60 days of age, followed by immunization once each in spring and autumn every year thereafter.

2 Reference Immunization Program for Multiparous Sows

2.1 Classical Swine Fever

Lapinized attenuated classical swine fever virus vaccine is administered once a year and should be inoculated during the non-pregnant period.

2.2 Swine Erysipelas

Attenuated swine erysipelas vaccine is administered once every six months (once each in spring and autumn. It is best to avoid vaccination during pregnancy).

2.3 Swine Pasteurellosis

Attenuated vaccine (oral or injection) is administered once each in March and September every year (it may also be administered before the local peak season for this disease).

2.4 Blue Ear Disease (PRRS), Pseudorabies, and Porcine Parvovirus Disease

Apply the "Blue-Parvo-Pseudo Triple Inactivated Vaccine" for immunization by intramuscular injection 3-4 weeks before mating.

2.5 Japanese Encephalitis

In epidemic areas, vaccination is carried out 1-2 months before mosquitoes and flies appear each year.

2.6 Piglet Yellow and White Scours

Use the "Piglet Escherichia coli ST1-LTB-K88 Trivalent Genetically Engineered Vaccine" with one intramuscular injection at 15 days before farrowing.

2.7 Piglet Red Scours

In threatened pig farms, the "Piglet Red Scours Inactivated Vaccine" or the "Piglet Red Scours Bivalent Genetically Engineered Vaccine" may be used. Inject once each at one month and half a month before farrowing.

2.8 Swine Streptococcosis

It is best to use the "Local Strain Inactivated Vaccine." In epidemic areas, immunize twice each in spring and autumn every year.

2.9 Swine Paratyphoid

Use the swine paratyphoid C500 attenuated vaccine to immunize (by injection or orally) once each in March and September every year.

2.10 Other Vaccines

For example, "Mycoplasmal Pneumonia Vaccine" and "Viral Diarrhea Vaccine" can be administered according to the vaccine instructions. To avoid immune interference between vaccines, two different vaccines should be administered at an interval of 7 days (except those explicitly stated as not interfering with or enhancing each other).

3 Reference Immunization Program for Replacement Gilts

3.1 Classical Swine Fever: Receive a third immunization before mating, and thereafter the same as for multiparous sows.

3.2 Blue Ear Disease (PRRS), Pseudorabies, and Porcine Parvovirus Disease

Apply the "Blue-Parvo-Pseudo Triple Inactivated Vaccine" for immunization by intramuscular injection 2-3 weeks before mating.

3.3 Piglet Yellow and White Scours

Use the "Piglet Escherichia coli ST1-LTB-K88 Trivalent Genetically Engineered Vaccine." First-farrowing sows receive one intramuscular injection each at 40 days and 15 days before farrowing.

4 Precautions for Vaccine Immunization

4.1 Immune Interference Issues

Other diseases can be handled according to the instructions for each disease vaccine: in principle, to prevent interference between vaccines, two different vaccines should be administered at an interval of at least 5-7 days (except those explicitly stated as not interfering with or enhancing each other).

4.2 Determining Immunization Timing

It is best to use immune monitoring as the scientific basis for determining immunization timing (vigorously promote immune monitoring technology for major diseases).

4.3 Improving and Maintaining "Immunization Quality"

Improve and maintain the "herd antibody uniformity" of the pig herd, and eliminate low-antibody susceptible pigs.

4.4 Environmental Cleanliness Issues

Make every effort to reduce the pathogen concentration (degree of pathogen contamination) in the external environment and maintain it dynamically over the long term (this can be done in conjunction with monitoring the degree of pathogen contamination), and eliminate the mistaken notion of "valuing immunization while neglecting disinfection."

4.5 Feed Issues

During oral administration of bacterial vaccines, do not feed distillers' grains, antibiotics, fermented sour swill, or high-heat feed, etc.

4.6 Medication Issues During Immunization

Within 5-7 days before and after immunization, avoid using drugs that have a negative impact on the vaccine immune response (such as chloramphenicol, tetracycline, and other drugs that can reduce white blood cells, or antibacterial drugs that have an inhibitory effect on bacterial vaccines, etc.).

4.7 Disinfection Issues During Immunization

When using various attenuated live vaccines for immunization (especially when using drinking water, feed mixing, or aerosol immunization), it is strictly prohibited to use various disinfectants for disinfection within 7-10 days before and after immunization (especially strictly prohibited are drinking water disinfection and spray or fumigation disinfection with pigs present).

4.8 Cross-Infection and Safe Injection Issues

4.8.1 Sterilization of Vaccination Equipment: Vaccination equipment (syringes, needles, etc.) must be strictly sterilized and disinfected according to requirements.

4.8.2 One Pig, One Needle: Strictly prohibit the "one needle to the end" injection method. It is best to achieve "one pig, one needle" (change the needle for each pig injected).

4.8.3 Order of Emergency Vaccination: During emergency immunization, proceed in the order of "relatively clean herd assumed healthy herd threatened herd affected herd." Within an affected herd, proceed in the order of "asymptomatic mild symptoms severe symptoms."

4.8.4 Safe and Scientific Injection: Intramuscular injection at the neck side behind the ear.

4.8.5 Immunization of Pregnant Sows: Under normal circumstances, immunization of sows during pregnancy should be avoided as much as possible (except for emergency immunization).