Which sulfonamide drugs should be used with caution in the treatment of infectious coryza in chickens?

The pathogen of infectious coryza in chickens is Haemophilus paragallinarum, and it is an acute upper respiratory tract disease with highly contagious transmission. The disease is prone to epidemics in humid seasons, mostly involves mixed infections, and the incidence is high in adult chickens.

Symptoms: nasal discharge, which forms scabs after drying and blocks the nostrils. Facial swelling, mostly swelling on one side of the face, head shaking, closed eyes and listlessness, tendency to lie down, decreased feed intake, decreased egg production, and greenish watery droppings. Some chickens show respiratory symptoms, coughing, sneezing, etc.

Treatment: sulfonamide drugs are highly effective, but they inhibit egg production, so they should be used with caution in laying hens; if used together with an equal amount of soda (sodium bicarbonate), the toxic side effects can be reduced. There are many drugs that can treat coryza in chickens, such as Gaolimixian, ciprofloxacin, Biyanke, etc., but relapse is easy after recovery, it is difficult to eradicate completely, and the treatment course is too long. A combined therapy of Chinese and Western medicines can be adopted, with a larger dosage, and the effect is remarkable. For example, use the Chinese herbal medicine Xinyi (biond magnolia flower bud), 2 grams per adult chicken per day; Cang'er (Siberian cocklebur fruit), 1 gram per adult chicken per day, decoct in water and give as drinking water, combined with tylosin, dissolving 1 gram in 10 kg of water, once daily, for 5 consecutive days. It should be noted that: if coryza has already broken out in the flock and the incidence is less than 1%, infectious coryza vaccine can still be administered at this time; if the incidence exceeds 5%, the infectious coryza vaccine must not be administered, in order to prevent worsening of the epidemic and the appearance of mass chicken deaths.