What are the prevention and treatment methods for furazolidone poisoning in pigs?

Furazolidone is commonly used to treat infectious diseases of the gastrointestinal tract, such as paratyphoid in piglets.

The dosage for pigs is 0.007 g per kg of body weight, given orally in 2 to 3 divided doses. Piglets are relatively sensitive to furazolidone, and when the fed dose is too large or it is used over a long period, it can cause acute or chronic poisoning. After poisoning, piglets show reduced appetite, weakness of the limbs, unsteady standing, swaying when walking, forelegs and hindlegs stretched outward, lowered skin temperature, slow responses, coma, and trembling of all body muscles. Necropsy of dead piglets reveals severe inflammation of the gastric fundus mucosa, with a band-shaped inflamed area running from the pylorus through the gastric fundus to the cardia, scattered with a small number of hemorrhagic spots of varying sizes, and the intestinal contents are golden yellow.

For this disease, emphasis should be placed on prevention; this type of drug must not be fed over a long period or in excessive amounts, and one treatment course is about 1 week. If poisoning in pigs is found, the medicated feed should be stopped immediately, and laxative-type drugs should be given to speed up the elimination of the toxin; feeding 2% sugar water (either brown sugar or white sugar is fine) has a very good effect on reducing symptoms. For severely affected pigs, 5% glucose-saline can be injected intraperitoneally or intravenously, and other drugs may be added as appropriate according to the actual situation.