What specific drug treats goose aspergillosis?

1. Outbreak situation

A certain @#@232@#@ household purchased 1000 goslings each on May 22, 1998, housed them in an outdoor plastic greenhouse shed, and fed them hybrid rice purchased from a grain depot. On June 18 and 19, more than 40 geese in the two flocks successively developed coughing. They were treated with oxytetracycline bulk powder, Baiyanqing and other drugs, but there was no improvement, and it spread to more than 100 geese, with severe cases even showing open-mouth breathing, a few with runny noses and head shaking, and about 30 geese in the flock had facial swelling. On the 21st, they were treated with erythromycin, livestock and poultry Chuankangding, ciprofloxacin and Miehuoling, but the disease was still progressing, and 4 sick geese were brought to the station for diagnosis. By this point, Liu XX's flock had 85 dead, with 85% of geese affected, and Zhou XX's flock had 103 dead, with 90% of geese affected.

2. Symptoms and lesions

The 4 sick geese had ruffled feathers, unstable standing, stretched necks and open-mouth breathing, and a harsh respiratory sound could be heard when approaching; a small amount of mucus was present in the nasal cavity (1 goose). No gross lesions were seen in the heart, liver or spleen, there was no intestinal inflammation, the trachea showed mild congestion (4 geese), the larynx had a small amount of fluid accumulation (2 geese), the thoracic cavity and air sacs were cloudy (4 geese), with scattered yellow nodules (3 geese), and millet-like nodules were seen on the thoracic wall and lungs. The nodules were single or paired or fused into masses, soft in texture, with the contents resembling bean curd residue (1 goose), while the entire lung tissue was hard in texture and had lost elasticity (3 geese).