What are the effects and benefits of perilla leaves
Perilla leaf, also known as su ye, chi su, zhou su and so on, is the leaf of the annual herbaceous plant perilla (Perilla frutescens) in the Lamiaceae family, genus Perilla. Used as medicine, it has the effects of releasing the exterior and dispelling cold, regulating qi and harmonizing the nutritive qi. It has a therapeutic effect on wind-cold colds, aversion to cold with fever, cough, asthma, chest and abdominal distension and fullness, and restless fetal movement, and can also neutralize fish and crab poisoning. Let us take a look at the effects and benefits of perilla leaves together below!
The medicinal effects of perilla leaves
[Nature and flavor] Pungent in flavor, slightly warm in nature, non-toxic.
[Meridian entry] Spleen and Lung meridians.
[Effects] Releases the exterior and dispels cold, regulates qi and harmonizes the nutritive qi. It mainly treats wind-cold colds, aversion to cold with fever, cough, asthma, chest and abdominal distension and fullness, and restless fetal movement, and can also neutralize fish and crab poisoning.
Medicinal combinations of perilla leaves
1. For exterior wind-cold attack with symptoms of aversion to cold and fever, headache without sweating, and nasal congestion with clear discharge, it can be combined with notopterygium rhizome, saposhnikovia root, angelica dahurica and so on to release the exterior and dispel cold.
2. For qi stagnation with dampness obstruction, disharmony of stomach qi, abdominal distension and oppression, and vomiting, nausea and diarrhea, it can be combined with ageratum, tangerine peel, pinellia fermented preparation, poria and so on to move qi, transform dampness and harmonize the middle.
Related discussions on perilla leaves
1. "Rihua Zi Bencao": Tonifies the middle and boosts qi. Treats distension and fullness of the heart and abdomen, stops cholera with cramps, opens the stomach and promotes food intake, and (treats) all cold qi, and stops beriberi.
2. "Luchanyan Bencao": Stops bleeding from metal wounds, treats hemorrhoids; wash with the decoction.
3. "Diannan Bencao": Induces sweating, relieves wind-attack headache, resolves phlegm, and relieves wheezing and asthma.
Pharmacological effects of perilla leaves
1. Antipyretic effect: Perilla leaf decoction and infusion at 2 g/kg administered orally to rabbits made febrile by typhoid mixed vaccine had a weak antipyretic effect.
2. Antibacterial effect: Perilla leaf can inhibit the growth of staphylococci in test tubes. The minimum inhibitory concentration of perilla leaf extract against 6 kinds of fungal agar cultures was 200-1600 mg/mL, and perillaldehyde in the extract plays the main antibacterial role.
3. Raising blood sugar: Perilla oil at 0.35 mL/kg given orally to rabbits can raise blood sugar. After the main component of the oil, perillaldehyde, is made into an oxime, its blood-sugar-raising effect is stronger than that of perilla oil.
4. Coagulation effect: Intravenous injection of perilla water extract into the marginal ear vein of rabbits can shorten blood coagulation time, plasma recalcification time and thromboplastin time, indicating that perilla has a promoting effect on the endogenous coagulation system.
6. Sedative effect: Perillaldehyde isolated from perilla leaves has a sedative effect and can prolong the sleep time of rats reduced by phenobarbital. Perilla water decoction at a 1:20 concentration has an inhibitory effect on the ECHO11 strain of virus.
Medicinal selected prescriptions of perilla leaves
1. To treat wind-attack fever: Perilla leaf, saposhnikovia root and Sichuan lovage rhizome 1 qian 5 fen each, tangerine peel 1 qian, licorice 6 fen. Add 2 slices of ginger and decoct for oral administration.
2. To treat sudden cold with upward qi: Dried perilla leaf 3 liang, aged tangerine peel 4 liang, wine 4 sheng, boil and take 1 sheng 5 ge, divided into two doses.
3. To treat cough with shortness of breath: Perilla stem and leaf (chopped) 1 liang, ginseng 0.5 liang. For the above two ingredients, coarsely crush and sieve. Take 3 qian bi per dose, water 1 zhan, decoct until reduced to 7 fen, remove the dregs, take warm, twice a day.
4. To treat hiccups during cold damage that do not stop: Red perilla 1 handful, water 3 sheng, boil and take 2 sheng, drink a little at a time.
5. To treat breast abscess with swelling and pain: Decoct perilla and take the decoction frequently, and also pound it and apply as a poultice.
6. To treat bleeding from metal wounds: Tender perilla leaves and mulberry leaves, pound together and apply.
7. To treat injuries from falls and blows: Pound perilla and apply; the wound will close by itself.
8. To treat snake bites: Pound perilla leaves to extract the juice and drink it.
Toxic and side effects of perilla leaves
The components of perilla, such as perilla ketone and other ketone compounds, are all 3-substituted furan compounds and show toxic effects on mice, goats and heifers, especially on the lungs, and can cause death due to pulmonary edema and pleural effusion. However, different routes of administration result in different toxicity. Perilla ketone at 10 mg/kg by intravenous injection can kill goats, while 40 mg/kg by gavage has no effect. Perilla alcohol has toxicity, irritancy and sensitizing effects. In addition, female goats can be killed by intravenous injection of perilla ketone at 10 mg/kg, but can still survive if given 40 mg/kg by gavage.
Clinical applications of perilla leaves
1. Treatment of chronic bronchitis: Take dried perilla leaves and a small amount of dried ginger (10:1) and prepare a 25% perilla leaf medicinal liquid. Take it once each morning and evening, 100 mL each time, with 10 days as one course of treatment. The interval between two courses is 3 days. A total of 552 cases were observed. After four courses, 62 cases were controlled in the short term, 150 cases showed marked effect, 213 cases improved, and 127 cases were ineffective.