What are the effects and uses of Selaginella doederleinii?

Selaginella doederleinii, also known as Di Ce Bai, Suoluo Cao, Jinlong Cao and so on, is the whole plant of Selaginella doederleinii, a plant of the genus Selaginella in the family Selaginellaceae. As a medicine it has the effects of clearing heat, detoxifying, fighting cancer and stopping bleeding, and it treats sore throat, red and swollen eyes, cough due to lung heat, mastitis, damp-heat jaundice, rheumatic arthralgia, bleeding from trauma and other conditions. Let us take a look at the effects and uses of Selaginella doederleinii below!
Medicinal Effects of Selaginella doederleinii
[Nature and Flavor] Sweet, slightly bitter and astringent in flavor, cool in nature.
[Meridians Entered] Lung and liver meridians.
[Effects] Clearing heat, detoxifying, fighting cancer and stopping bleeding; mainly treats sore throat, red and swollen eyes, cough due to lung heat, mastitis, damp-heat jaundice, rheumatic arthralgia and bleeding from trauma.
Pharmacological Effects of Selaginella doederleinii
1. The alkaloids contained in Selaginella doederleinii have a fairly good inhibitory effect on mouse sarcoma S180. When a Selaginella doederleinii preparation was given by gavage to mice with experimental liver cancer for 12 consecutive days, although it had no inhibitory effect on the tumor, it could significantly prolong the survival days of the animals. After dissection it was found that the animals in the medication group had hypertrophy of the zona fasciculata of the adrenal cortex, while the tissues of the brain, heart, lung and kidney were normal.
2. The water extract of Selaginella doederleinii has an inhibitory effect on murine retrovirus reverse transcriptase and human DNA polymerase; the 50% inhibitory concentration (IC5O) for reverse transcriptase is 10 micrograms/ml, and the 50% inhibitory concentration (IC50) for DNA polymerase is 9.0 micrograms/ml. Another experiment proved that an acidic substance extracted from Selaginella doederleinii has cytotoxic activity.
Clinical Applications of Selaginella doederleinii
Take 300 grams of Selaginella doederleinii, wash the above medicine, add water and decoct 2 times, 3 hours each time, combine the decoctions, filter, concentrate, add ethanol until the alcohol content is 80%, let stand for 24 hours, filter to remove the precipitate, recover the ethanol from the filtrate, concentrate again into a paste, add an appropriate amount of starch to make a soft mass, granulate, dry and press into tablets, obtaining 1000 tablets, each tablet containing 0.3 grams of the crude drug. It clears heat, detoxifies and fights cancer, and is used for choriocarcinoma, lung cancer, throat cancer and cancers of the digestive tract. Oral administration, adults 7 tablets each time, 3 times a day.
Medicinal Selected Formulas of Selaginella doederleinii
1. To treat pneumonia, acute tonsillitis and conjunctivitis: 30 grams of Selaginella doederleinii, add 30 grams of lean pork, decoct in water and take.
2. To treat hepatitis: Longlin Cao, Tu'er Cai, Chasi Ma and Juhua 30 grams each, Wuzhua Jinying 10 grams, decoct in water and take.
3. To treat red and swollen eyes: 30 grams of Selaginella doederleinii, 30 grams of Qianliguang, 15 grams of dandelion. Decoct in water and take.
4. To treat chronic hepatitis: Selaginella doederleinii and Hedyotis diffusa 30 grams each. Decoct in water and take.
5. To treat cuts and bleeding from trauma: grind Selaginella doederleinii into a fine powder and apply externally to the affected area.
6. To treat rheumatism: equal amounts of Daye Cai and Wupi Feng. Decoct in water for fumigation and washing.