Bronchopneumonia may be associated with common variable immunodeficiency
Immunodeficiency is one of the causes of bronchopneumonia, because people know very little about how immunodeficiency makes one susceptible to bronchopneumonia. In fact, the immunodeficiency system discussed here is still a huge topic. Specifically, it includes thirteen categories such as congenital X-linked agammaglobulinemia, common variable immunodeficiency, selective immunoglobulin deficiency, and complement deficiency due to complement deficiency (very rare).
Bronchopneumonia
And immunodeficiency, just like an allergic constitution being susceptible to allergic asthma, becomes one of the main factors that easily induce bronchopneumonia. Because there are as many as thirteen categories of immunodeficiency, this forms various types of bronchopneumonia populations and symptom manifestations. For example, congenital X-linked agammaglobulinemia among immunodeficiencies increases sensitivity to pathogenic bacteria, leading to susceptibility to lower respiratory tract infections.
Congenital X-linked agammaglobulinemia among immunodeficiencies also easily leads to gastrointestinal and bone and joint infections, and also increases susceptibility to sepsis, meningitis, etc., but in terms of symptom manifestations and severity of onset, it is not as severe as sepsis caused by other reasons. It also has characteristics such as being chronic, slow to resolve, and recurrent. The susceptible bacteria are Staphylococcus aureus, Streptococcus, etc., and more than 50% of patients will develop bronchiectasis.
Classification of bronchopneumonia
In common variable immunodeficiency, most bronchopneumonia patients have normal or increased numbers of B lymphocytes, which cannot develop into secretory plasma cells; in some cases, B lymphocytes do not proliferate, or synthesize immunoglobulin. In some cases of bronchopneumonia with common variable immunodeficiency, there is an increase in suppressor T lymphocytes, and the significance of this is still unclear, and so on.
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