How to prevent and treat linear hepatic hemorrhage disease in farmed pufferfish

[Symptoms of linear hepatic hemorrhage disease in pufferfish] Sick pufferfish have a darkened body color, with the color from in front of the eyes to the snout noticeably paler; sometimes the body color of the pufferfish becomes pale while the area in front of the eyes becomes even paler and pallid. Sometimes the bases of the caudal fin, anal fin and dorsal fin are congested. When the abdomen of the fish is cut open, 1—2 obvious linear blood stasis marks can be seen on the liver, all extending upward from the left side of the abdomen to the right side. There is no food in the intestine, and the intestinal wall is sometimes slightly congested; sometimes severely affected fish show unusually frantic, random darting behavior, similar to the symptoms of white mouth disease in pufferfish. Linear hepatic hemorrhage disease in pufferfish has a high mortality rate, and there is currently no effective treatment method, so we adopt the policy of giving priority to prevention with treatment as a supplement. Regulate the water environment well, frequently siphon out waste, and frequently change the water, especially the bottom layer of water, which should be replaced regularly. When sick fish are found, remove and destroy them promptly. The following treatment measures were taken for the affected ponds and achieved certain results.

[Prevention and treatment methods for linear hepatic hemorrhage disease in pufferfish](1) Splashing drugs into the water: ① Splash 0.5—0.8 mg/L oxytetracycline hydrochloride; ② Splash 0.1 mg erythromycin. ③ Splash 0.4—0.5 mg/L furazolidone. (2) Medicated bait feeding: ① Add 0.4—0.5 g norfloxacin per kg of bait and mix into the bait, feeding continuously for 5 days; ② Mix 0.1—0.3 g oxytetracycline hydrochloride per kg of feed into the bait and feed.